Clues for the word "PAIN"
We've had 177 crossword clues used for this word, and seen it 418 times in crosswords. It was last seen in Daily American crossword on March 11, 2026.
Definition of pain
- n. - Punishment suffered or denounced; suffering or evil inflicted as a punishment for crime, or connected with the commission of a crime; penalty.
- n. - Any uneasy sensation in animal bodies, from slight uneasiness to extreme distress or torture, proceeding from a derangement of functions, disease, or injury by violence; bodily distress; bodily suffering; an ache; a smart.
- n. - Specifically, the throes or travail of childbirth.
- n. - Uneasiness of mind; mental distress; disquietude; anxiety; grief; solicitude; anguish.
- n. - See Pains, labor, effort.
- n. - To inflict suffering upon as a penalty; to punish.
- n. - To put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture; as, his dinner or his wound pained him; his stomach pained him.
- n. - To render uneasy in mind; to disquiet; to distress; to grieve; as a child's faults pain his parents.
Referring Clues
- Excedrin target
- Annoyance
- Hurt
- Nuisance
- Cause to grimace
- Neuralgia
- What an analgesic stops
- Bother
- Cause of a wince
- Feeling that makes you say "Ow!"
- Number's target?
- Ibuprofen target
- Baby brother, often
- Result of punishment
- Pill
- Pest
- Aspirin target
- Tylenol target
- Reason to take acetaminophen
- Pesky kid
- Suffering partner?
- Neck ailment?
- Annoying person
- "No ___, no gain"
- That hurts
- Analgesic target
- "Royal" nuisance
- Analgesic's target
- Grief
- French bread
- Partner of suffering
- Botheration
- Stitch, e.g.
- It "clings cruelly to us," according to Keats
- Arduous chore
- "No ___, no gain"
- It can be chronic or shooting
- Anguish
- Aleve target
- ___ in the neck (pest)
- Hassle
- Bratty kid
- Annoying sort
- Bothersome task
- Prerequisite for gain?
- Some athletes play through it
- Clubber Lang's prediction for Rocky
- Grimace inducer
- Emotional distress
- It might be in the neck
- Suffering partner
- Prerequisite for a weightlifter's gain?
- No gain without it
- Charley horse, e.g.
- Endorphins producer
- Suffering's partner, in court
- "Royal" annoyance
- Big bother
- Requisite for gain, so they say
- What lines with stars at the end indicate in comics
- See 1-Across
- Royal annoyance
- ___ in the neck (pest)
- T-___ (noted Auto-Tune user)
- Vexation
- Distress
- "No ___, no gain" (gym saying)
- ___ in the neck
- Agony
- Major nuisance
- Major nuisance
- Sibling, at times?
- Annoyance
- Aspirin's target
- Ache
- Unpleasant sensation
- Reason for a clinic visit
- It may be unbearable
- Major hassle
- Young brother, often
- Reliever's target
- What a dolorimeter measures
- Little brother, at times
- Bread, in Bruxelles
- "I feel your ___"
- Nuisance, so to speak
- Advil target
- It hurts
- Liniment target
- Proverbial problem for the neck or butt
- Physical suffering
- Bothersome person
- Bodily distress
- Pesky one
- Percocet's target
- Tylenol's target
- Physical discomfort
- Suffering
- Major inconvenience
- What acupuncture relieves, for some
- Big hassle
- A ___in the neck
- Bread, to Fifi
- Annoying inconvenience
- Injury result, perhaps
- Annoyance, so to speak
- Big nuisance
- Charley horse consequence
- Major annoyance
- Pang
- Twinge
- What a toothache causes
- Suffering with father at home
- Bodily suffering
- Jimmy Eat World "It takes my ___ away"
- To spill a nip can hurt!
- Indigestion, say, caused by French bread
- Dad in distress
- Punishment one really feels
- Suffering state dismissed head
- What a pin could cause
- How a pin can hurt!
- Seizing a sharp object does hurt
- Dad has some measure of suffering
- What nociceptors sense
- Cause of some grimacing
- Patient quality that may be measured by a facial analogue scale
- There's no gain without it
- Ouch inducer
- What an analgesic treats
- Cause of grimacing
- Tough person to tolerate
- Acute discomfort
- Suffering keeps father at home
- Suffering, ache
- Bothersome annoying person
- Applied for protection, with no end of trouble
- More than discomfort
- What analgesics relieve
- Royal annoyance?
- Suffering light that's pronounced
- Irksome sort
- Considerable inconvenience
- No gain? No this
- Icy Hot target
- ___ in the neck (annoyance)
- Soreness
- It might make you smart
- With 71-Across, Bengay's purpose ... or this puzzle's theme
- Total hassle
- It's often evaluated on a :) to :( scale
- Royal problem?
- Counterpart of pleasure
- Pill ... or a reason to take a pill
- Total inconvenience
- Salonpas target
- Sharp ache
- Dad's not out of trouble
- Wong To Yick target
- Reason for applying a medicated plaster
- Reason to keep rubbing one's back
- Discomfort cause
- Reason for using a heating pad
- Real hassle
- Royal ___
- Something necessary for gain, they say
- A backache is one
- Apt rhyme for "sprain"
- Discomfort
- Reason for using an ice pack
- Hurt feelings?
- That caused by a pin in the wrong place?
- What Tylenol targets
- Total headache
- What aspirin relieves
- Cause of a grimace
- What Excedrin relieves
Last Seen In
- Daily American - March 11, 2026
- Evening Standard Easy - March 03, 2026
- New York Times - February 08, 2026
- Mirror Daily - December 26, 2025
- Penny Dell Sunday - September 28, 2025
- Daily American - September 20, 2025
- LA Times - August 02, 2025
- Daily Cryptic - May 30, 2025
- Mindfood Daily - May 06, 2025
- Daily American - May 01, 2025
- Your Life Choices - April 14, 2025
- King Syndicate - Eugene Sheffer - March 31, 2025
- LA Times - March 27, 2025
- Mirror Daily - March 08, 2025
- Penny Dell Sunday - February 23, 2025
- King Syndicate - Eugene Sheffer - January 17, 2025
- New York Times - December 31, 2024
- Penny Dell Daily - December 10, 2024
- Mirror Daily - December 01, 2024
- Daily American - November 26, 2024
- Penny Dell Daily - November 21, 2024
- New Zealand Herald - November 16, 2024
- Daily American - October 15, 2024
- King Syndicate - Thomas Joseph - September 27, 2024
- Penny Dell Daily - September 17, 2024
- USA Today - September 14, 2024
- Penny Dell Daily - August 29, 2024
- Daily American - August 26, 2024
- LA Times - August 25, 2024
- New York Times - August 18, 2024
- And in 388 more crossword puzzles...